HEADSHIP HISTORY OF OSEI KYERETWIE SENIOR HIGH SCHOOLS
| S/N | NAME | FROM | TO |
| 1 | Mr. George Bray | 1962 | 1976 |
| 2 | Mr. Bossman Owusu Ayim | 1976 | 1982 |
| 3 | Mr. Kwaku Baah | 1982 | 1983 |
| 4 | Mr. Frederick Acheampong | 1983 | 2001 |
| 5 | Mr. K. Opuni Boakye | 2001 | 2009 |
| 6 | Dr. Samuel Agyepong | 2009 | 2015 |
| 7 | Mrs. Mary Cromwell Owusu | 2015 | 2018 |
| 8 | Mr Andrews Boateng | 2018 | 2020 |
| 9 | Mr. Michael Mensah | 2020 | 2025 |
| 10 | Mr. Frederick Keelson-Aikins | 2025 | To date |
